Yanhong Gao
Chinese PLA General Hospital
China
Title: Establishment and verification of miRNAs expression molecules for breast cancer and its distant metastasis
Biography
Biography: Yanhong Gao
Abstract
Breast cancer is one of malignant tumors in women. Distant metastasis is the main death cause for breast cancer patients. The early detection of laboratory is the key for prevention and therapy breast cancer. MicroRNAs are a large class of single-strand endogenous non-coding small RNA. It was reported that cells may release tumor endogenous microRNAs into peripheral blood cycle and become circulating microRNAs in tumor genesis and development. We have analysed serum microRNAs of breast cancer and breast cancer metastasis patients by new screening strategy and biostatistics method. We have got hsa-miR-6090 and hsa-miR-451a as candidated molecules of breast cancer and breast cancer metastasis. Therefore, we speculate that hsa-miR-6090, hsa-miR-451a play an important role in the development and metastasis of breast cancer, and further study to verify their biological function will be go on.
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